Olaparib Treatment Before Surgery Proves Feasible in BRCA-Mutant Ovarian Cancer

Neoadjuvant treatment with olaparib prior to surgical resection and adjuvant chemotherapy was well tolerated and led to a 100% optimal resection rate in patients with newly diagnosed, BRCA-mutant ovarian, primary peritoneal, or fallopian tube cancer.

This is an edited version of an article by Carolyn Seymour published in OncLive Mar. 28, 2023

Dana-Farber Research Supports FDA Approval of New Therapy for Certain Patients with Ovarian Cancer

Mirvetuximab soravtansine has been approved by the FDA for the treatment of recurrent platinum-resistant high-grade serous ovarian cancer that highly expresses the folate receptor alpha. Clinical testing of this new therapy has been co-led by Dr Ursula Matulonis, MD.

This is an edited version of a news release published by Dana Farber Cancer Institute on Nov. 14, 2022

FDA Approves Mirvetuximab Soravtansine For Treatment of Ovarian Cancer

On November 14, 2022, the FDA granted accelerated approval to mirvetuximab soravtansine for the treatment of adult patients with folate receptor α (Frα)–positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer, who have received 1 to 3 prior systemic treatment regimens.

This is an edited version of an article written by Caroline Seymour and published in OncLive Nov. 15, 2022